Skip navigation links
About Us
Fellows in Training
Allied Health Professionals
Patients & Public
ACAAI Foundation
Annual Meeting
Skip navigation links
About Us
About Us Home Page
The Specialty
American Medical Association Code of Ethics
Membership Categories | Membership in ACAAI
Become a Member
Become an International Affiliate Member
College History, Leadership & Awards
ACAAI Privacy Policy
ACAAI Terms of Use
Contact Us
Non-Members Online Store
Medical Student Resources
Clinical Trial Resource
Member Directory
ACAAI Leadership
Annual Meeting
Joint Task Force of Practice Parameters
College History: Leadership & Awards
Letters to the Web Editors
Meetings and Events Calendar
Fellows in Training
FIT Home Page
FIT Become a Member
Meetings and Events
Member & Patient-Related Organizations
Nomination Procedures
FITs Unite in Baltimore for Education and Networking
Resources help FITs prepare for the ABAI exam
Allied Health Professionals
Allied Health Home Page
Annual Meeting
Ask the Allergist
Patient Frequently Asked Questions
Member & Patient Related Links
Meetings & Events Calendar
Become a Member
Alliance Home Page
Annual Meeting
About the ACAAI Alliance
Meetings & Events Calendar
Become a Member
Alliance Calling all Photo Buffs!
Patients & Public
ACAAI Foundation
ACAAI Foundation Home Page
Foundation News
Donor Honor Roll
ACAAI Foundation Tithe-A-Talk Program
Honor and Memorial Gifts
Annual Meeting
ACAAI - Faces Facets Allergy Immunology 2014
Al Jarreau
Named Lectures
Practice management, literature review and more for allied health professionals
Board Review

Your Questions about Vitamin D, Answered!

Q. Who should have vitamin D blood tests?

A. Presently, it is not recommended that all individuals have annual vitamin blood tests. However, it is appropriate for certain subsets of the population to have routine assessment of vitamin D levels. It is appropriate to determine vitamin D levels in the following individuals:
• Pregnant women
• Infants who are exclusively breastfed
• Individuals with autoimmune diseases
• Individuals with allergic disorders
• Individuals with asthma
• Individuals with immunodeficiency
• Individuals who have very little sun exposure
• Individuals who cover their skin year-round
• Individuals with dark skin
• Individuals who are obese
• Individuals who are ≥ 70 years old
• Individuals who have gut malabsorption syndromes
• Individuals who have risk factors for developing cancer
• Individuals who live north of the 37th parallel

Q. How often should vitamin D levels be checked?

A. An annual baseline vitamin D level is considered to be appropriate for the above individuals. If the vitamin D level is low, then a vitamin D supplement should be started and the vitamin D level should be re-checked in 6 to 8 weeks. If the vitamin D blood level has risen to normal, then the vitamin D supplementation should be continued with annual or semi-annual assessment of vitamin D levels.

Q. What is considered to be an optimal vitamin D level?

A. The current parameters defining “normal” vitamin D levels are based on maintaining normal calcium-bone-phosphate homeostasis. There is no universal agreement on what vitamin D levels are ideal in all individuals in all age brackets. The most commonly accepted vitamin D level parameters used by most reference laboratories in the United States are those developed by the Endocrine Society. Whether these cut points represent vitamin D levels for optimal immunomodulatory, antimicrobial, and paracrine function is unknown at this time and is an area being intensively researched. The Endocrine Society has defined the following serum vitamin D-25-hydroxy parameters:
• 0 – 19 ng/mL (deficiency)
• 20 – 29 ng/mL (insufficiency)
• 30 – 100 ng/mL (sufficiency)


1) Holick, MF et al. Endocrine Society. Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab, 2011; 96(7): 1911-1930.

2) Holick, MF. Vitamin D and health: Evolution, biologic functions, and recommended dietary intakes of vitamin D. In Vitamin D: Physiology, molecular biology, and clinical applications. By Holick, MF. Humana Press, 2010.

3) Plum, LA and Deluca, HF. The functional metabolism and molecular biology of vitamin D action. In Vitamin D: Physiology, molecular biology, and clinical applications. By Holick, MF. Humana Press, 2010.

4) Institute of Medicine, Food and Nutrition Board. Dietary Reference Intakes for Calcium and Vitamin D. Washington, DC: National Academy Press, 2010.

5) Bjelakovic, G et al. Vitamin D supplementation for prevention of mortality in adults. Cochrane Database Syst. Rev. 2011 July 6; (7): CD007470.doi:10.1002/14651858.CD007470.pub2.
Copyright 2012 - American College of Allergy, Asthma & Immunology | 85 West Algonquin Road, Suite 550 | Arlington Heights, IL 60005

website designed and maintained by Washington Graphic Services